PDE4-IN-29
PDE4-IN-29 (Compound 55) is an orally active and selective PDE4 inhibitor (including subtypes such as PDE4A1, PDE4B2, PDE4D3) with IC50s of <5 nM against PDE4D3. PDE4-IN-29 inhibits the degradation of cyclic adenosine monophosphate (cAMP), increases intracellular cAMP levels, suppressing the release of inflammatory factors such as TNF-α. PDE4-IN-29 is promising for research of inflammatory diseases including psoriasis, atopic dermatitis, and chronic obstructive pulmonary disease.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2815361-45-4
- Formel: C27H34N2O8S
- Molecular Weight:546.63
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
PDE4A1 |
PDE4B2 |
PDE4D3 |
Chemical Information
-
CAS. Nr. 2815361-45-4
-
Molecular Weight 546.63
-
Formel C27H34N2O8S
-
SMILES
O=C1N([C@@H](C2=CC(OCC)=C(OC)C=C2)CS(C)(=O)=O)C(C3=C(NC(C)=O)C=CC(C(CCCC)O)=C31)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PDE4-IN-29 Related Classifications
HY-176520 Related Classifications
Powered by Bioz