STE11
The STE11 subfamily gathers MAP3K-level enzymes of the STE group, homologous to yeast Ste11, that sit at the apex of MAPK cascades. Members include the MEKK1-4 kinases, mixed-lineage kinases, TAO kinases, and ZAK, all sharing a C-terminal STE11-type kinase domain with variable N-terminal regulatory regions such as PH, CRIB, leucine-rich repeat, or leucine-zipper modules. They respond to stresses, Rho GTPases, or receptor inputs and phosphorylate MEK/MKK-family kinases to drive JNK, p38, and ERK signaling that governs proliferation, apoptosis, and inflammation. Recombinant STE11 kinases are widely used in cascade reconstitution and inhibitor screening.
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STE11 Recombinant Proteins (9)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
