Ramifenazone-d7
Ramifenazone-d7 is the deuterium labeled Ramifenazone. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities.
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- CAS. Nr.: 1330180-51-2
- Formel: C14H12D7N3O
- Molecular Weight:252.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1330180-51-2
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Unlabeled Cas 3615-24-5
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Molecular Weight 252.36
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Formel C14H12D7N3O
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SMILES
O=C1N(N(C)C(C)=C1NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])C2=CC=CC=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Bhupender Nehra, et al. Recent advancements in the development of bioactive pyrazoline derivatives. Eur J Med Chem. 2020 Nov 1;205:112666. [Content Brief]
[3]. R Surendra Kumar, et al. Anti-inflammatory and antimicrobial activities of novel pyrazole analogues. Saudi J Biol Sci. 2016 Sep;23(5):614-20. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)