rG4 WT_AHPC_PEG2

rG4 WT_AHPC_PEG2 (30 nM; 30 min) binds to the RHAU53 peptide with a K_d of 67.5 nM, demonstrating strong molecular recognition of the DHX36 fragment^[1].
rG4 WT_AHPC_PEG2 (40 nM; 30 min) binds to full-length DHX36 protein with a K_d of 79.7 nM, verifying robust target recognition^[1].
rG4 WT_AHPC_PEG2 (3.75-500 nM; 24 h) induces proteasome-dependent degradation of DHX36 in HeLa cells, achieving over 90% degradation at 62.5 nM after 24 h and >50% degradation within 6 h at 50 nM^[1].
rG4 WT_AHPC_PEG2 (15.6-500 nM; 24 h) reduces endogenous APP protein levels in HeLa cells in a concentration-dependent manner, correlating with DHX36 degradation^[1].
rG4 WT_AHPC_PEG2 (50-200 nM; 24 h) induces proteasome-dependent degradation of DHX36 and concentration-dependent reduction of Gnai2 protein in mouse C2C12 myoblast cells^[1].
rG4 WT_AHPC_PEG2 (200 nM; 24 h) impairs the proliferative capacity of mouse C2C12 myoblast cells and skeletal muscle stem cells by reducing EdU incorporation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.