Ruboxyl
Ruboxyl is an anthracycline antibiotic with antitumor activity. Ruboxyl inhibits colorectal cancer (CRC) liver metastasis in mice by 84%, suppresses B16 melanoma growth, and increases the survival rate of mice with L1210 or L5178Y leukemia.
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- CAS. Nr.: 80214-88-6
- Formel: C36H47ClN4O10
- Molecular Weight:731.23
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 80214-88-6
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Molecular Weight 731.23
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Formel C36H47ClN4O10
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SMILES
O=C1C2=C(C3=C(C(O)=C2C(C4=C1C=CC=C4OC)=O)[C@@H](O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)C[C@@](/C(C)=N\N=C6CC(C)(N(C(C)(C/6)C)O)C)(O)C3)O.Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Leonetti C, et al. Ruboxyl, a new nitroxyl derivative of daunorubicin - acute toxicity and antitumor effect in animals. Int J Oncol. 1993 Oct;3(4):615-8. [Content Brief]
[2]. Sirovich I, et al. Activity of ruboxyl, a nitroxyl derivative of daunorubicin, on experimental models of colorectal cancer metastases. Tumour Biol. 1999 Sep-Oct;20(5):270-6. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Ruboxyl Related Classifications
HY-119261 Related Classifications
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