(S)-Pomalidomide
(S)-Pomalidomide ((S)-CC-4047) is an angiogenesis-inhibiting drug with growth-inhibitory activity against B-cell tumors. (S)-Pomalidomide can induce complete tumor regression in BurKitt lymphoma cells. (S)-Pomalidomide serves as an immunomodulator with potential applications in inhibiting hematological malignancies.
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- CAS. Nr.: 202271-89-4
- Formel: C13H11N3O4
- Molecular Weight:273.24
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
3.9 nM
Compound: (S)-5a
|
Inhibition of lipopolysaccharide stimulated TNF-alpha release in human PBMC
Inhibition of lipopolysaccharide stimulated TNF-alpha release in human PBMC
|
[PMID: 10386948] |
Chemical Information
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CAS. Nr. 202271-89-4
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Molecular Weight 273.24
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Formel C13H11N3O4
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SMILES
O=C1N([C@@H](CC2)C(NC2=O)=O)C(C3=C1C=CC=C3N)=O
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Synonyms
(S)-CC-4047
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)