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Art. -Nr.: HY-W040167

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VPC 23153

VPC 23153 is a S1P₄ receptor agonist and vasoconstrictor. VPC 23153 activates the S1P₄ receptor, thereby triggering vasoconstriction. VPC 23153 induces pulmonary artery contraction. VPC 23153 can be used in studies related to pulmonary arterial hypertension.

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CAS. Nr.: 787582-98-3
Formel: C₁₇H₂₈N₃O₄P
Molecular Weight:369.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

VPC 23153 Chemical Structure

CAS. Nr.: 787582-98-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- In Vitro
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Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

S1PR4

Alle LPL Receptor Isoform-spezifische Produkte anzeigen :

In Vitro

VPC 23153 (0.01-3 μM) induces dose-dependent vasoconstriction in isolated perfused normotensive rat lungs^[1].
VPC 23153 (0.1-10 μM) induces concentration-dependent contraction of isolated pulmonary arteries (but not renal or mesenteric arteries) from chronically hypoxic rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 787582-98-3
Molecular Weight 369.40
Formel C₁₇H₂₈N₃O₄P
SMILES

[C@@H](COP(=O)(O)O)(N)C=1NC=2C(N1)=CC=C(CCCCCCCC)C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Ota H, et al. S1P(4) receptor mediates S1P-induced vasoconstriction in normotensive and hypertensive rat lungs. Pulm Circ. 2011;1(3):399-404. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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VPC 23153

Alle LPL Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

VPC 23153 Related Classifications

HY-W040167 Related Classifications