Insulin (human)
Based on 95 publication(s) in Google Scholar
Insulin (human) is a polypeptide hormone that regulates the level of glucose. Insulin (human) can be used for the diabetes mellitus.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.92%
- CAS No.: 11061-68-0
- Formule: C257H383N65O77S6
- Masse moléculaire:5807.57
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Stockage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Insulin (human)
More- Signal Transduct Target Ther. 2025 Nov 4;10(1):361. [Abstract]
- Cell. 2026 Mar 5;189(5):1323-1340.e25. [Abstract]
- Cell. 2025 Jan 9;188(1):157-174.e22. [Abstract]
- Mol Cancer. 2024 Jan 10;23(1):12. [Abstract]
- Cancer Commun (Lond). 2021 Jul;41(7):576-595. [Abstract]
- Nat Commun. 2025 Mar 8;16(1):2319. [Abstract]
- Nat Commun. 2023 Nov 23;14(1):7643. [Abstract]
- Acta Pharm Sin B. 2025 Nov 13.
- Autophagy. 2026 May 17:1-23.
- Adv Sci (Weinh). 2025 Apr 15:e2415846. [Abstract]
- Theranostics. 2022 Nov 7;12(18):7699-7716. [Abstract]
- Theranostics. 2020 Mar 26;10(10):4705-4719. [Abstract]
- Cardiovasc Res. 2019 Aug 1;115(10):1533-1545. [Abstract]
- Metabolism. 2024 Mar:152:155769. [Abstract]
- Food Chem. 2026 Apr 6:12:100401.
- Cell Death Dis. 2025 Dec 22;16(1):918. [Abstract]
- Adv Healthc Mater. 2025 Jun 10:e2500946. [Abstract]
- Acta Biomater. 2022 Mar 15:141:89-101. [Abstract]
- Cell Death Dis. 2020 Nov 4;11(11):950. [Abstract]
- Cell Death Dis. 2020 Jun 19;11(6):475. [Abstract]
- Proc Natl Acad Sci U S A. 2026 Jul 7;123(27):e2523789123.
- J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13649. [Abstract]
- Osteoarthritis Cartilage. 2026 Feb 6:S1063-4584(26)00648-5. [Abstract]
- Int J Biol Macromol. 2024 Nov;281(Pt 3):136498. [Abstract]
- Int J Biol Macromol. 2024 Apr 15;267(Pt 2):131645. [Abstract]
- Int J Biol Macromol. 2024 Feb 5;262(Pt 1):129875. [Abstract]
- Int J Biol Macromol. 2023 Dec 2;257(Pt 1):128588. [Abstract]
- Phytomedicine. 2025 Oct 11:148:157400. [Abstract]
- Phytomedicine. 2024 Jun:128:155404. [Abstract]
- Phytomedicine. 2022 Apr:98:153959. [Abstract]
- Apoptosis. 2026 Feb 2;31(2):63. [Abstract]
- Emerg Microbes Infect. 2025 Jan 2:2447620. [Abstract]
- Biomed Pharmacother. 2020 Jul;127:110155. [Abstract]
- Food Sci Hum Wellness. 2025.
- Stem Cell Res Ther. 2023 Dec 20;14(1):333. [Abstract]
- Cell Rep. 2025 Nov 18;44(12):116577. [Abstract]
- Cell Rep. 2025 May 7;44(5):115682. [Abstract]
- Appl Surf Sci. 2020, 145332.
- J Med Chem. 2026 Jan 22;69(2):1698-1709. [Abstract]
- J Med Chem. 2024 Sep 12;67(17):15387-15410. [Abstract]
- Clin Transl Med. 2022 Jul;12(7):e989. [Abstract]
- Mol Med. 2025 May 14;31(1):188. [Abstract]
- Phytother Res. 2026 May;40(5):2417-2436. [Abstract]
- Transl Psychiatry. 2022 Mar 29;12(1):130. [Abstract]
- Cell Biol Toxicol. 2025 May 15;41(1):85. [Abstract]
- Food Biosci. 2024 Dec.
- Biochem Pharmacol. 2020 Aug;178:114038. [Abstract]
- Chem Biol Interact. 2022 Feb 25:354:109798. [Abstract]
- Cells. 2026 Feb 11;15(4):329. [Abstract]
- Commun Biol. 2025 Dec 16;8(1):1774. [Abstract]
- Commun Biol. 2024 Oct 18;7(1):1348. [Abstract]
- Polymers. 2026 Jan;18(13):1562.
- Int J Mol Sci. 2024 Sep 29;25(19):10514. [Abstract]
- Genes Nutr. 2024 Aug 24;19(1):17. [Abstract]
- Int J Mol Sci. 2023 Jun 26;24(13):10661. [Abstract]
- Front Pharmacol. 2022 Feb 15;13:779715. [Abstract]
- mBio. 2025 Dec 10;16(12):e0255425. [Abstract]
- J Mol Cell Cardiol. 2024 Jun 4:S0022-2828(24)00086-5. [Abstract]
- Biol Res. 2024 Nov 24;57(1):90. [Abstract]
- Front Endocrinol. 2021 Apr 27;12:663530. [Abstract]
- Eur J Pharm Biopharm. 2025 Jan 15:114629. [Abstract]
- Bioengineered. 2022 Mar;13(3):7485-7499. [Abstract]
- J Lipid Res. 2026 Feb;67(2):100981. [Abstract]
- Toxics. 2024 Mar 14;12(3):214. [Abstract]
- Nutr Metab. 2024 Jan 2;21(1):2. [Abstract]
- iScience. 2023 Feb 28;26(4):106289. [Abstract]
- Sci Rep. 2025 Nov 6;15(1):38865. [Abstract]
- Fish Shellfish Immunol. 2022 Sep:128:474-483. [Abstract]
- Oncol Rep. 2020 Aug;44(2):577-588. [Abstract]
- J Proteome Res. 2025 Oct 14. [Abstract]
- Biology (Basel). 2025 Jun 17;14(6):712. [Abstract]
- Food Chem Toxicol. 2019 Dec;134:110830. [Abstract]
- Am J Physiol Renal Physiol. 2023 Dec 1;325(6):F870-F884. [Abstract]
- Phytochemistry. 2022 Mar:195:113073. [Abstract]
- Cell Transplant. 2025 Jan-Dec:34:9636897251376125. [Abstract]
- J Pharm Pharmacol. 2025 Sep 10:rgaf081. [Abstract]
- Naunyn Schmiedebergs Arch Pharmacol. 2025 Nov 21. [Abstract]
- Am J Physiol Endocrinol Metab. 2024 May 1;326(5):E696-E708. [Abstract]
- Genet Sel Evol. 2024 Apr 9;56(1):28. [Abstract]
- Naunyn Schmiedebergs Arch Pharmacol. 2021 Jan;394(1):205-216. [Abstract]
- Cell Biol Int. 2019 May;43(5):553-564. [Abstract]
- J Orthop Surg Res. 2025 Nov 14;20(1):997. [Abstract]
- Mol Cell Biol. 2025 Jul 22:1-17. [Abstract]
- Immun Inflamm Dis. 2023 Nov;11(11):e1071. [Abstract]
- Electron J Biotechnol. 2025 Aug 13.
- Chin J Integr Med. 2025 Jun 14. [Abstract]
- Mutat Res. 2025 Jun 11:831:111911. [Abstract]
- STAR Protoc. 2025 Sep 26;6(4):104115. [Abstract]
- Res Sq. 2025 Oct 27.
- Res Sq. 2025 Aug 11.
- Patent. US20250154468A1.
- Patent. US20250109168A1.
- bioRxiv. 2024 September 07.
- Research Square Preprint. 2022 Jul.
- J Biomater Tissue Eng. September 2021.
Customer Validation & Images
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
Activité biologique
The human insulin gene contains two intervening sequences, one is within the region transcribed into the 5'-untranslated segment of the mRNA and the other interrupts the C-peptide encoding region[1]. Human insulin is commonly used to treat type 2 diabetes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Slc35d3-Flox mice and Slc35d3-wild type mice injected with 100 mg/mLl D-Glucose (HY-B0389)[1]
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Dosage:0.75 U/kg
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Administration:ip; once
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Result:Significantly lowers blood glucose levels.
Chemical Information
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CAS No. 11061-68-0
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Appearance Solid
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Masse moléculaire 5807.57
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Formule C257H383N65O77S6
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Color White to off-white
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (95)
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Journal Impact Factor
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Most Recent
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Signal Transduct Target Ther
Olverembatinib, a multikinase inhibitor that modulates lipid metabolism, in advanced succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 1b study and translational research. [Abstract]2025 Nov 4;10(1):361. PMID: 41184234
Insulin (human) purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Nov 4;10(1):361. [Abstract]
Tissues from GIST patient samples were digested and resuspended in GIST primary cell culture medium, 1% Anti-Anti, 50 ng/mL SCF, 125 ng/mL EGF, 20 ng/mL bFGF (HY-P7004), 25 ng/mL Hydrocortisone (HY-N0583), and 5 µg/mL Insulin. Olverembatinib inhibited lipid droplet accumulation and lipid uptake in SDH-deficient GIST primary cells and downregulated CD36 in primary SDH-deficient GIST cells..
Insulin (human) purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Nov 4;10(1):361. [Abstract]
Tissues from GIST patient samples were digested and resuspended in GIST primary cell culture medium, 1% Anti-Anti, 50 ng/mL SCF, 125 ng/mL EGF, 20 ng/mL bFGF (HY-P7004), 25 ng/mL Hydrocortisone (HY-N0583), and 5 µg/mL Insulin. Olverembatinib inhibited lipid droplet accumulation and lipid uptake in SDH-deficient GIST primary cells and downregulated CD36 in primary SDH-deficient GIST cells.
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Cell
Sympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin. [Abstract]2026 Mar 5;189(5):1323-1340.e25. PMID: 41616781 -
Cell
Intermittent fasting triggers interorgan communication to suppress hair follicle regeneration. [Abstract]2025 Jan 9;188(1):157-174.e22. PMID: 39674178 -
Mol Cancer
Organoids derived from patients provide a new opportunity for research and individualized treatment of malignant peritoneal mesothelioma. [Abstract]2024 Jan 10;23(1):12. PMID: 38200517 -
Cancer Commun (Lond)
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma. [Abstract]2021 Jul;41(7):576-595. PMID: 34110104 -
Nat Commun
2025 Mar 8;16(1):2319. PMID: 40057489 -
Nat Commun
2023 Nov 23;14(1):7643. PMID: 37996411 -
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Adv Sci (Weinh)
Asprosin-FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development. [Abstract]2025 Apr 15:e2415846. PMID: 40231957 -
Theranostics
SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex. [Abstract]2022 Nov 7;12(18):7699-7716. PMID: 36451857
Insulin (human) purchased from MedChemExpress. Usage Cited in: Theranostics. 2022 Nov 7;12(18):7699-7716. [Abstract]
For insulin tolerance tests, mice on HFD for 15 weeks received an intraperitoneal injection of Insulin (1.0 U/kg body weight) after 6 hours of fasting. Glucose level was measured in tail blood at 0, 15, 30, 60, 90, and 120 mins after glucose or insulin injection using a glucometer.
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Theranostics
2020 Mar 26;10(10):4705-4719. PMID: 32292524
Insulin (human) purchased from MedChemExpress. Usage Cited in: Theranostics. 2020 Mar 26;10(10):4705-4719. [Abstract]
Insulin tolerance tests (ITT) were performed by intraperitoneally injecting Insulin (0.75 unit/kg in 0.9% wt/vol saline) to mice that had been fasted for 6 h. Blood glucose levels were measured at 0, 15, 30, 60, and 120 minutes using an Infinity glucose meter.
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Cardiovasc Res
Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts. [Abstract]2019 Aug 1;115(10):1533-1545. PMID: 30649212 -
Metabolism
Ubiquitination of cytoplasmic HMGB1 by RNF186 regulates hepatic lipophagy in non-alcoholic fatty liver disease. [Abstract]2024 Mar:152:155769. PMID: 38158076 -
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Cell Death Dis
2025 Dec 22;16(1):918. PMID: 41430036 -
Adv Healthc Mater
2025 Jun 10:e2500946. PMID: 40492897 -
Acta Biomater
Construction of adipose tissue using a silica expander capsule and cell sheet-assembled of decellularized adipose tissue. [Abstract]2022 Mar 15:141:89-101. PMID: 34974176 -
Cell Death Dis
LncRNA LHFPL3-AS1 contributes to tumorigenesis of melanoma stem cells via the miR-181a-5p/BCL2 pathway. [Abstract]2020 Nov 4;11(11):950. PMID: 33149126 -
Cell Death Dis
The lncRNA RP11-142A22.4 promotes adipogenesis by sponging miR-587 to modulate Wnt5β expression. [Abstract]2020 Jun 19;11(6):475. PMID: 32561739 -
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J Cachexia Sarcopenia Muscle
The Stimulator of Interferon Genes Deficiency Attenuates Diabetic Myopathy Through Inhibiting NLRP3-Mediated Pyroptosis. [Abstract]2025 Feb;16(1):e13649. PMID: 39602084 -
Osteoarthritis Cartilage
Silence of Linc01152 promotes chondrogenic differentiation and facilitates cartilage repair through directly increasing SOX9 expression. [Abstract]2026 Feb 6:S1063-4584(26)00648-5. PMID: 41655689 -
Int J Biol Macromol
Hepatic-derived extracellular vesicles in late pregnancy promote mammary gland development by stimulating prolactin receptor-mediated JAK2/STAT5/mTOR signalling. [Abstract]2024 Nov;281(Pt 3):136498. PMID: 39393720 -
Int J Biol Macromol
Mechanistic insights into the role of USP14 in adipose tissue macrophage recruitment and insulin resistance in obesity. [Abstract]2024 Apr 15;267(Pt 2):131645. PMID: 38631582 -
Int J Biol Macromol
Linc-smad7 is involved in the regulation of lipid synthesis in mouse mammary epithelial cells. [Abstract]2024 Feb 5;262(Pt 1):129875. PMID: 38320638 -
Int J Biol Macromol
Phyllostachys nigra (Lodd. ex Lindl.) derived polysaccharide with enhanced glycolipid metabolism regulation and mice gut microbiome. [Abstract]2023 Dec 2;257(Pt 1):128588. PMID: 38048922 -
Phytomedicine
Perillyl alcohol ameliorates high-fat diet-induced obesity in mice by modulating gut microbiota and activating IRF4-mediated brown fat thermogenesis. [Abstract]2025 Oct 11:148:157400. PMID: 41138577 -
Phytomedicine
Compound Danshen Dripping Pill effectively alleviates cGAS-STING-triggered diseases by disrupting STING-TBK1 interaction. [Abstract]2024 Jun:128:155404. PMID: 38507852 -
Phytomedicine
Amelioration of lipid accumulations and metabolism disorders in differentiation and development of 3T3-L1 adipocytes through mulberry leaf water extract. [Abstract]2022 Apr:98:153959. PMID: 35134622 -
Apoptosis
SEMA3E promotes beige adipocyte differentiation and thermogenesis via β-catenin signaling in mice. [Abstract]2026 Feb 2;31(2):63. PMID: 41627586 -
Emerg Microbes Infect
SARS-CoV-2 and HCoV-OC43 regulate host m6A modification via activation of the mTORC1 signaling pathway to facilitate viral replication. [Abstract]2025 Jan 2:2447620. PMID: 39745173 -
Biomed Pharmacother
Dehydroabietic acid alleviates high fat diet-induced insulin resistance and hepatic steatosis through dual activation of PPAR-γ and PPAR-α. [Abstract]2020 Jul;127:110155. PMID: 32413669 -
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Stem Cell Res Ther
Hypertonicity induces mitochondrial extracellular vesicles (MEVs) that activate TNF-α and β-catenin signaling to promote adipocyte dedifferentiation. [Abstract]2023 Dec 20;14(1):333. PMID: 38115136 -
Cell Rep
Blocking glycogen synthase 1 in white adipose tissue alleviates hypermetabolism following severe burn injury through inhibition of JAK2 by UDPG. [Abstract]2025 Nov 18;44(12):116577. PMID: 41259203 -
Cell Rep
Mitochondrial GCN5L1 coordinates with YME1L and MICOS to remodel mitochondrial cristae in white adipocytes and modulate obesity. [Abstract]2025 May 7;44(5):115682. PMID: 40338741 -
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J Med Chem
High-Throughput Screening of Natural Products Alleviating Diabetic Nephropathy Using a Peroxynitrite (ONOO-) Responsive Fluorescent Probe. [Abstract]2026 Jan 22;69(2):1698-1709. PMID: 41480733 -
J Med Chem
2024 Sep 12;67(17):15387-15410. PMID: 39159497 -
Clin Transl Med
Cancer-associated fibroblast-derived exosomal microRNA-20a suppresses the PTEN/PI3K-AKT pathway to promote the progression and chemoresistance of non-small cell lung cancer. [Abstract]2022 Jul;12(7):e989. PMID: 35857905 -
Mol Med
Arctiin, a lignan compound, enhances adipose tissue browning and energy expenditure by activating the adenosine A2A receptor. [Abstract]2025 May 14;31(1):188. PMID: 40369420 -
Phytother Res
Polydatin Targets ACADVL to Combat Obesity by Promoting Adipocyte Browning and Activating Fatty Acid Oxidation. [Abstract]2026 May;40(5):2417-2436. PMID: 41696894 -
Transl Psychiatry
Human forebrain organoids reveal connections between valproic acid exposure and autism risk. [Abstract]2022 Mar 29;12(1):130. PMID: 35351869 -
Cell Biol Toxicol
IGFBP3 enhances adipose-derived stem cell function in soft tissue injury repair via ITGB1 and ERK pathway activation. [Abstract]2025 May 15;41(1):85. PMID: 40369223 -
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Biochem Pharmacol
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer. [Abstract]2020 Aug;178:114038. PMID: 32422139 -
Chem Biol Interact
E3 ubiquitin ligase RNF180 reduces sensitivity of triple-negative breast cancer cells to Gefitinib by downregulating RAD51. [Abstract]2022 Feb 25:354:109798. PMID: 34998818 -
Cells
The Asp-Encoding Gene FBN1 Mediates Cold Adaptation in Sunite Sheep by Reprogramming Adipocyte Differentiation Towards Thermogenesis. [Abstract]2026 Feb 11;15(4):329. PMID: 41744772 -
Commun Biol
In vivo imaging reveals exosome-mediated intercellular communication in lens development. [Abstract]2025 Dec 16;8(1):1774. PMID: 41402507 -
Commun Biol
Nr-CWS regulates METTL3-mediated m6A modification of CDS2 mRNA in vascular endothelial cells and has prognostic significance. [Abstract]2024 Oct 18;7(1):1348. PMID: 39424634 -
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Int J Mol Sci
The SIRT5-Mediated Upregulation of C/EBPβ Promotes White Adipose Tissue Browning by Enhancing UCP1 Signaling. [Abstract]2024 Sep 29;25(19):10514. PMID: 39408844 -
Genes Nutr
Protective effects of Nogo-B deficiency in NAFLD mice and its multiomics analysis of gut microbiology and metabolism. [Abstract]2024 Aug 24;19(1):17. PMID: 39182019 -
Int J Mol Sci
PER2 Promotes Odontoblastic/Osteogenic Differentiation of Dental Pulp Stem Cells by Modulating Mitochondrial Metabolism. [Abstract]2023 Jun 26;24(13):10661. PMID: 37445839 -
Front Pharmacol
Thymopentin-Mediated Inhibition of Cancer Stem Cell Stemness Enhances the Cytotoxic Effect of Oxaliplatin on Colon Cancer Cells. [Abstract]2022 Feb 15;13:779715. PMID: 35242031 -
mBio
Human-specific activation of the DUX4-SLC34A2 axis by herpesviruses suppresses antiviral innate immunity. [Abstract]2025 Dec 10;16(12):e0255425. PMID: 41211819 -
J Mol Cell Cardiol
Role of 8-hydroxyguanine DNA glycosidase 1 deficiency in exacerbating diabetic cardiomyopathy through the regulation of insulin resistance. [Abstract]2024 Jun 4:S0022-2828(24)00086-5. PMID: 38844061 -
Biol Res
Perturbation of mammary epithelial cell apicobasal polarity by RHBDF1-facilitated nuclear translocation of PKCζ. [Abstract]2024 Nov 24;57(1):90. PMID: 39582014 -
Front Endocrinol
ADP Induces Blood Glucose Through Direct and Indirect Mechanisms in Promotion of Hepatic Gluconeogenesis by Elevation of NADH. [Abstract]2021 Apr 27;12:663530. PMID: 33986729 -
Eur J Pharm Biopharm
Thumb-sized 3D-Printed cymbal microneedle array (CyMA) for enhanced transdermal drug delivery. [Abstract]2025 Jan 15:114629. PMID: 39824326 -
Bioengineered
Circular RNA hsa_circ_0011324 is involved in endometrial cancer progression and the evolution of its mechanism. [Abstract]2022 Mar;13(3):7485-7499. PMID: 35259044 -
J Lipid Res
2026 Feb;67(2):100981. PMID: 41565113 -
Toxics
Differential Disruption of Glucose and Lipid Metabolism Induced by Phthalates in Human Hepatocytes and White Adipocytes. [Abstract]2024 Mar 14;12(3):214. PMID: 38535947 -
Nutr Metab
2024 Jan 2;21(1):2. PMID: 38166933 -
iScience
Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity. [Abstract]2023 Feb 28;26(4):106289. PMID: 36968079 -
Sci Rep
FZD6 mediates the contributing role of miR-199a-5p in the adipogenesis of bone marrow mesenchymal stem cells derived from aplastic anemia. [Abstract]2025 Nov 6;15(1):38865. PMID: 41198743 -
Fish Shellfish Immunol
Structural insights into the redox regulation of Oncomelania hupensis TRP14 and its potential role in the snail host response to parasite invasion. [Abstract]2022 Sep:128:474-483. PMID: 35988710 -
Oncol Rep
TNF‑α promotes the malignant transformation of intestinal stem cells through the NF‑κB and Wnt/β‑catenin signaling pathways. [Abstract]2020 Aug;44(2):577-588. PMID: 32627006 -
J Proteome Res
Comprehensive Characterization of Disulfide Bonds in Insulin and Its Metabolites from Liver S9 by a Proteomic Method. [Abstract]2025 Oct 14. PMID: 41084413 -
Biology (Basel)
3-Hydroxyacyl CoA Dehydratase 2 Is Essential for Embryonic Development and Hepatic Metabolic Function Under a Low-Fat, High-Carbohydrate Diet. [Abstract]2025 Jun 17;14(6):712. PMID: 40563962 -
Food Chem Toxicol
α-Humulene inhibits hepatocellular carcinoma cell proliferation and induces apoptosis through the inhibition of Akt signaling. [Abstract]2019 Dec;134:110830. PMID: 31562948 -
Am J Physiol Renal Physiol
Neuropilin 1 Promotes Unilateral Ureteral Obstruction-Induced Renal Fibrosis via RACK1 in Renal Tubular Epithelial Cells. [Abstract]2023 Dec 1;325(6):F870-F884. PMID: 37823194 -
Phytochemistry
2022 Mar:195:113073. PMID: 34974412 -
Cell Transplant
Adipose-derived stem cells inhibit dendritic cell migration by secreting tumor necrosis factor-α-stimulated gene 6 to improve the allogeneic skin transplantation survival rate in mice. [Abstract]2025 Jan-Dec:34:9636897251376125. PMID: 41108126 -
J Pharm Pharmacol
Aucubin inhibits the activity of lung cancer stem-like cells by targeting degradation of β-catenin. [Abstract]2025 Sep 10:rgaf081. PMID: 40928458 -
Naunyn Schmiedebergs Arch Pharmacol
Alisol B 23-acetate alleviates high-fat diet-induced insulin resistance by activating the SIRT1/FOXO1 axis and PI3K/AKT pathway. [Abstract]2025 Nov 21. PMID: 41269296 -
Am J Physiol Endocrinol Metab
Glycogen synthesis is required for adaptive thermogenesis in beige adipose tissue and affects diet-induced obesity. [Abstract]2024 May 1;326(5):E696-E708. PMID: 38568151 -
Genet Sel Evol
Constructing eRNA-mediated gene regulatory networks to explore the genetic basis of muscle and fat-relevant traits in pigs. [Abstract]2024 Apr 9;56(1):28. PMID: 38594607 -
Naunyn Schmiedebergs Arch Pharmacol
GLUT1 participates in tamoxifen resistance in breast cancer cells through autophagy regulation. [Abstract]2021 Jan;394(1):205-216. PMID: 32500187 -
Cell Biol Int
Regulation of insulin resistance by targeting the insulin-like growth factor 1 receptor with microRNA-122-5p in hepatic cells. [Abstract]2019 May;43(5):553-564. PMID: 30958584 -
J Orthop Surg Res
RNA-sequencing-based elucidation of the mechanism underlying aFGF mediated regulation of BMSCs via the PI3K-AKT pathway and its implications for rotator cuff injury repair. [Abstract]2025 Nov 14;20(1):997. PMID: 41239461 -
Mol Cell Biol
miR-365-3p Regulates Gastrointestinal Dysfunction in Diabetes Mellitus Rats via the TLR4/MyD88/NF-κB Pathway. [Abstract]2025 Jul 22:1-17. PMID: 40693422 -
Immun Inflamm Dis
Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF-1 pathway. [Abstract]2023 Nov;11(11):e1071. PMID: 38018587 -
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Chin J Integr Med
Pseudolaric Acid B Alleviates Non-alcoholic Fatty Liver Disease by Targeting PPARα to Regulate Lipid Metabolism and Promote Mitochondrial Biogenesis. [Abstract]2025 Jun 14. PMID: 40515882 -
Mutat Res
A novel mechanism in driving non-small cell lung cancer progression: The METTL3/FOXA1/PTK2 cascade. [Abstract]2025 Jun 11:831:111911. PMID: 40541037 -
STAR Protoc
Protocol for stromal vascular fraction isolation from inguinal subcutaneous white adipose tissue and beige adipocyte differentiation. [Abstract]2025 Sep 26;6(4):104115. PMID: 41014562 -
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Solvant et solubilité
H2O : 10 mg/mL (1.72 mM; ultrasonic and adjust pH to 2 with HCl)
1 M Acetic acid : ≥ 10 mg/mL (1.72 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
The following protocol is derived from the literature and is for reference only. It is recommended to first try a small sample.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureté et documentation
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Fiche technique (270 KB)
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SDS (397 KB)
- English - EN (397 KB)
- Français - FR (397 KB)
- Deutsch - DE (397 KB)
- Norwegian - NO (397 KB)
- Español - ES (397 KB)
- Swedish - SV (397 KB)
- Italian - IT (397 KB)
- Korean - KR (397 KB)
- Portuguese - PT (397 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Hongrui Wang, et al. SLC35D3 promotes white adipose tissue browning to ameliorate obesity by NOTCH signaling. Nat Commun. 2023 Nov 23;14(1):7643. [Content Brief]
[2]. Tseng CH, et al. Prolonged use of human insulin increases breast cancer risk in Taiwanese women with type 2 diabetes. BMC Cancer. 2015 Nov 4;15:846. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / 1 M Acetic acid | 1 mM | 0.1722 mL | 0.8609 mL | 1.7219 mL | 4.3047 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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