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Cat. No.: HY-149344

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Anticancer agent 133

Anticancer agent 133 (compound Rh2) is an anti-cancer agent with cytotoxic and antimetastatic activities. Anticancer agent 133 induces cell cycle arrest, apoptosis, and autophagy. Anticancer agent 133 also inhibits cell metastasis via suppression of EGFR expression mediated by FAK-regulated integrin β1.

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CAS No.: 2758905-51-8
Formule: C₂₄H₁₉Cl₃N₅ORh
Masse moléculaire:602.71

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Data Sheet (276 KB)

Anticancer agent 133 Chemical Structure

CAS No.: 2758905-51-8

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Chemical Information

CAS No. 2758905-51-8
Masse moléculaire 602.71
Formule C₂₄H₁₉Cl₃N₅ORh
SMILES

Cl[Rh]12(Cl)([N]#CC)[N]3=C(C(N2C4=CC=CC=C4)=O)C(Cl)=CC=C3N5C(C6=CC=CC=C6)=CC(C)=[N]51
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

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COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
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MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
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Références

[1]. Gu YQ, et al. Rhodium(III)-Picolinamide Complexes Act as Anticancer and Antimetastasis Agents via Inducing Apoptosis and Autophagy. J Med Chem. 2023 Jul 27;66(14):9592-9606. [Content Brief]

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Anticancer agent 133

Voir tous les produits spécifiques à Isoform EGFR

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Chemical Information

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Anticancer agent 133 Related Classifications

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