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Cat. No.: HY-111037

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BMS-457

BMS-457 is a potent and selective CCR1 antagonist. BMS-457 can be used in the study of rheumatoid arthritis.

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CAS No.: 946594-19-0
Formule: C₂₄H₃₅ClN₂O₄
Masse moléculaire:451.00

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

BMS-457 Chemical Structure

CAS No.: 946594-19-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

BMS-457 is a potent and selective CCR1 antagonist. BMS-457 can be used in the study of rheumatoid arthritis^[1].

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Chemical Information

CAS No. 946594-19-0
Masse moléculaire 451.00
Formule C₂₄H₃₅ClN₂O₄
SMILES

O[C@@]1(C2=CC=C(C=C2)Cl)C(C)(CN(CC1)C([C@@H](C(C)C)NC([C@@H]3CC[C@H](C3)O)=O)=O)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Gardner DS, et al. The discovery of BMS-457, a potent and selective CCR1 antagonist. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3833-40. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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BMS-457

Voir tous les produits spécifiques à Isoform CCR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

BMS-457 Related Classifications

HY-111037 Related Classifications