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Cat. No.: HY-172619

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BS-153

BS-153 is a novel synthetic oxazolidinone agent with anti-inflammatory activities by blocking the activation of the NF-κB/PKCθ pathway. BS-153 inhibits the expression levels of iNOS and COX-2 and pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) on LPS-stimulated RAW264.7 cells.

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CAS No.: 1935692-54-8
Formule: C₂₇H₂₆ClF₃N₆O₂
Masse moléculaire:558.98

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

BS-153 Chemical Structure

CAS No.: 1935692-54-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

CAS No. 1935692-54-8
Masse moléculaire 558.98
Formule C₂₇H₂₆ClF₃N₆O₂
SMILES

FC(F)(F)C1=C(NC(C2=CC=C(N3CCC(N4CCOCC4)CC3)C(C#N)=C2)=O)C=NN1C5=CC=C(Cl)C=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Liyan Xu, et al. A novel synthetic oxazolidinone derivative BS-153 attenuated LPS-induced inflammation via inhibiting NF-κB/pkcθ signaling pathway. Fish Shellfish Immunol. 2025 Jun:161:110292. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
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Références

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BS-153

Voir tous les produits spécifiques à Isoform NF-κB