CP-664511
CP-664511 is an orally active and potent α4β1 integrin antagonist with anti-inflammatory effects (IC50=0.52 nM). CP-664511 inhibits the interaction between α4β1 and vascular cell adhesion molecule-1 (VCAM-1), significantly reducing eosinophil infiltration into lung tissue. CP-664511 is promising for research of asthma and allergic airway diseases.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 379692-00-9
- Formule: C28H34N4O6
- Masse moléculaire:522.59
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
α4β1 0.52 nM (IC50) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
0.69 nM
Compound: 22
|
Inhibition of Alpha4-beta1 integrin in Jurkat cells
Inhibition of Alpha4-beta1 integrin in Jurkat cells
|
[PMID: 11551757] |
Chemical Information
-
CAS No. 379692-00-9
-
Masse moléculaire 522.59
-
Formule C28H34N4O6
-
SMILES
O=C(O)CCC1=CC([C@@H](NC(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C(OC)=C2)=O)CC(C)C)=NO1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP-664511 Related Classifications
HY-119142 Related Classifications
Powered by Bioz