Dicranin
Dicranin is a 15-lipoxygenase (15-LOX) inhibitor and bacterial agent. Dicranin inhibits the dioxygenation reaction of polyenoic fatty acids by irreversibly binding to lipoxygenase. Dicranin can be isolated from the phospholipids of Philonotis fontana, Leptodontium paradoxum, and Dicranum scoparium. Dicranin can be used in studies related to Gram-positive bacterial infections.
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- CAS No.: 61481-30-9
- Formule: C18H26O2
- Masse moléculaire:274.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
15-LOX |
In Vitro
Dicranin (10-200 μg/mL; up to 24 h) acts as a bactericide against Bacillus cereus (down to 150 μg/mL) and Bacillus stearothermophilus (at 200 μg/mL), with time-dependent bactericidal/bacteriostatic effects at intermediate concentrations, weak growth inhibition against Bacillus stearothermophilus at 10 μg/mL, no activity against Bacillus cereus at 10 μg/mL[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 61481-30-9
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Masse moléculaire 274.40
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Formule C18H26O2
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SMILES
CC/C=C\C/C=C\C/C=C\CC#CCCCCC(O)=O
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Structure Classification
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)