DTriP-22
DTriP-22 is a highly potent and low-toxicity inhibitor of enterovirus 71 3D polymerase (EV71 3D polymerase). DTriP-22 exhibits broad-spectrum anti-RNA virus activity (particularly against picornaviruses) beyond EV71, but shows no activity against DNA viruses. DTriP-22 acts at the early stage of viral replication and exerts its function by specifically inhibiting viral RNA synthesis. DTriP-22 can be used in anti-enterovirus research.
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- CAS No.: 717098-99-2
- Formule: C27H25BrN6S
- Masse moléculaire:545.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RD | CC50 |
100 μM
Compound: DTriP-22
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Cytotoxicity against human RD cells after 16 hrs by MTS-based assay
Cytotoxicity against human RD cells after 16 hrs by MTS-based assay
|
[PMID: 19414569] |
Chemical Information
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CAS No. 717098-99-2
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Masse moléculaire 545.50
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Formule C27H25BrN6S
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SMILES
BrC1=C(C(N2CCN(CC2)C3=C(C=NN4C5=CC=CC=C5)C4=NC=N3)C6=C(C)C=CS6)C=CC=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)