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Cat. No.: HY-162667

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EX05

EX05 is a potent KIF18A inhibitor with an IC₅₀ value of 8.2 nM. EX05 has the potential for the research of cancer.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2892307-20-7
Formule: C₂₆H₃₀F₂N₄O₅S
Masse moléculaire:548.60

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

EX05 Chemical Structure

CAS No.: 2892307-20-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

EX05 is a potent KIF18A inhibitor with an IC₅₀ value of 8.2 nM. EX05 has the potential for the research of cancer^[1].

IC₅₀ & Target

IC₅₀: 8.2 nM (KIF18A)^[1]

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Chemical Information

CAS No. 2892307-20-7
Masse moléculaire 548.60
Formule C₂₆H₃₀F₂N₄O₅S
SMILES

O=C1N(C2CC(F)(F)C2)N=C(N3C(C(C=CC(NS(=O)(CCO)=O)=C4)=C4C5(CCC6(CC6)CC5)C3)=O)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xing Ding, et al. Spiro derivative as kif18a inhibitor. WO2024108765A1.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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EX05

Voir tous les produits spécifiques à Isoform Kinesin

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

EX05 Related Classifications

HY-162667 Related Classifications