Ganomycin I
Ganomycin I is a dual inhibitor of α-Glucosidase and HMG-CoA reductase. Ganomycin I can also inhibits HIV protease. Ganomycin I exhibits anti-diabetic and anti-osteoclastogenesis effects.
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- CAS No.: 1191255-15-8
- Formule: C21H26O4
- Masse moléculaire:342.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 1191255-15-8
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Masse moléculaire 342.43
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Formule C21H26O4
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SMILES
OC1=C(C=C(C=C1)O)[C@@]2([H])C=C(C(O2)=O)CC/C=C(C)/CC/C=C(C)/C
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Structure Classification
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Initial Source
Ganoderma colossum
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Tran PT, et, al. Ganomycin I from Ganoderma lucidum attenuates RANKL-mediated osteoclastogenesis by inhibiting MAPKs and NFATc1. Phytomedicine. 2019 Mar 1;55:1-8. [Content Brief]
[2]. Wang K, et, al. Structural Modification of Natural Product Ganomycin I Leading to Discovery of a α-Glucosidase and HMG-CoA Reductase Dual Inhibitor Improving Obesity and Metabolic Dysfunction in Vivo. J Med Chem. 2018 Apr 26;61(8):3609-3625. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)