CFAP53 - cilia and flagella associated protein 53 Gene

Also Known as HTX6; CCDC11

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 220136

Summary

This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning. [provided by RefSeq, Aug 2015]

CFAP53 Products (1)

mRNA Protein Name
NM_145020.5 NP_659457.2 cilia- and flagella-associated protein 53

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Références Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
26538025 GOA
involved in determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
26531781 GOA
Cellular Component GO Annotation Evidence Références Source
located in axonemal microtubule IDA
IDA: Inferred from direct assay
36191189 GOA
located in axoneme IDA
IDA: Inferred from direct assay
25504577 GOA
located in centriolar satellite IDA
IDA: Inferred from direct assay
26538025 GOA
located in ciliary transition zone IDA
IDA: Inferred from direct assay
26538025 GOA
located in spindle pole IDA
IDA: Inferred from direct assay
26538025 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cilia- and flagella-associated protein 53

  • coiled-coil domain containing 11

CFAP53 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
CFAP53 Q96M91 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
32296183
Intra
CFAP53 Q96M91 CCHCR1 Homo sapiens Q8TD31-3
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
CFAP53 Q96M91 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
CFAP53 Q96M91 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra
CFAP53 Q96M91 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
CFAP53 Q96M91 PNMA1 Homo sapiens Q8ND90
Validated Y2H
25416956
Intra
CFAP53 Q96M91 TNIP1 Homo sapiens Q15025
Y2H Prey Pooling
25416956
Intra
CFAP53 Q96M91 TNIP1 Homo sapiens Q15025
Y2H Array
25416956
Intra
CFAP53 Q96M91 TNIP1 Homo sapiens Q15025
Validated Y2H
25416956
Intra
CFAP53 Q96M91 MYOG Homo sapiens P15173
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 MYOG Homo sapiens P15173
Y2H Array
32296183
Intra
CFAP53 Q96M91 PARVG Homo sapiens Q9HBI0
Validated Y2H
32296183
Intra
CFAP53 Q96M91 RABEP1 Homo sapiens Q15276
Y2H Array
32296183
Intra
CFAP53 Q96M91 RABEP1 Homo sapiens Q15276
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 HIP1 Homo sapiens O00291
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 HIP1 Homo sapiens O00291
Y2H Array
32296183
Intra
CFAP53 Q96M91 GRIPAP1 Homo sapiens Q4V328
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 GRIPAP1 Homo sapiens Q4V328
Y2H Array
32296183
Intra
CFAP53 Q96M91 LENG8 Homo sapiens Q96PV6
Validated Y2H
32296183
Intra
CFAP53 Q96M91 CEP70 Homo sapiens Q8NHQ1
Y2H Array
25416956
Intra
CFAP53 Q96M91 TRIM23 Homo sapiens P36406
Validated Y2H
25416956
Intra
CFAP53 Q96M91 TRIM23 Homo sapiens P36406
Y2H Array
25416956
Intra
CFAP53 Q96M91 TRIM23 Homo sapiens P36406
Y2H Prey Pooling
25416956
Intra
CFAP53 Q96M91 HMG20A Homo sapiens Q9NP66
Validated Y2H
25416956
Intra
CFAP53 Q96M91 HMG20A Homo sapiens Q9NP66
Y2H Prey Pooling
25416956
Intra
CFAP53 Q96M91 LDOC1 Homo sapiens O95751
Y2H Prey Pooling
32296183
Intra
CFAP53 Q96M91 LDOC1 Homo sapiens O95751
Y2H Array
32296183
Intra
CFAP53 Q96M91 SH2D4A Homo sapiens Q9H788
Validated Y2H
32296183
Intra
CFAP53 Q96M91 CBY1 Homo sapiens Q9Y3M2
Y2H Prey Pooling
25416956
Intra
CFAP53 Q96M91 CBY1 Homo sapiens Q9Y3M2
Validated Y2H
25416956
Intra
CFAP53 Q96M91 CBY1 Homo sapiens Q9Y3M2
Y2H Array
25416956
Intra
CFAP53 Q96M91 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
CFAP53 Q96M91 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS02554 CFAP54 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02555 CFAP57 Human Pre-designed siRNA Set A Pre-designed Set / Unkown