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Cat. No.: HY-125727

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Globosuxanthone A

Globosuxanthone A is a dihydroxanthenone with obvious antifungal activity towards Fusarium graminearum, Fusarium solani, and Botrytis cinerea with MIC values of 4, 8, and 16 μg/mL, respectively. Anticancer activity.

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CAS No.: 917091-74-8
Formule: C₁₅H₁₂O₇
Masse moléculaire:304.25

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Globosuxanthone A Chemical Structure

CAS No.: 917091-74-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

In Vitro

Globosuxanthone A shows cytotoxicities against NCI-H460, MCF-7, SF-268, PC-3, PC-3M, LNCaP, DU-145 cells (IC₅₀=0.65-3.6 µM)^[1].
Globosuxanthone A impairs cell cycle progression of NCI-H460 and PC-3M cells leading to accumulation in the G2/M and S phases ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 917091-74-8
Masse moléculaire 304.25
Formule C₁₅H₁₂O₇
SMILES

O=C([C@@]1(O)C(C2=O)=C(OC3=C2C(O)=CC=C3)C=C[C@H]1O)OC
Structure Classification
- Phenols
- Monophenols
- Phenols
- Xanthones
Initial Source
- Endogenous metabolite
- Human Gut Microbiota Metabolites
- Microorganisms
Microdiplodia sp
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Miao C, et al. Antifungal xanthones produced by the endophytic fungus Paraconionthyrium sp. YM 311593. Folia Microbiol (Praha). 2020;65(3):567-572. [Content Brief]

[2]. Wijeratne EM, et al. A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity. Bioorg Med Chem. 2006;14(23):7917-7923. [Content Brief]

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Globosuxanthone A

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Sphinganine-C17

K858 (Racemic)

Glyceryl 1-monooctanoate

Lydicamycin

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β-Defensin-4 (human)

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Alisertib (Standard)

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Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

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