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Nesvacumab

(Synonyms: REGN910)
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Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1. Nesvacumab can be used in vascular researches.

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  • Pureté : 99.11%
  • CAS No.: 1296818-77-3
  • Masse moléculaire:144.86 kDa
  • Stockage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Nesvacumab
  • Experimental Validation Results for Nesvacumab
  • Experimental Validation Results for Nesvacumab
  • Nesvacumab Chemical Structure
    Nesvacumab Chemical Structure
CAS No.: 1296818-77-3
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Nesvacumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Angiopoietin-2 Protein, Human can bind Nesvacumab. The EC50 for this effect is 19.65 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 TF-1 cells with Nesvacumab (HY-P99036, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.

  • Nesvacumab Chemical Structure
    1/16
  • Nesvacumab
  • Immobilized Angiopoietin-2 Protein, Human can bind Nesvacumab. The EC50 for this effect is 19.65 ng/mL.
  • Flow cytometric analysis of 1X106 TF-1 cells with Nesvacumab (HY-P99036, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.