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Cat. No.: HY-121491

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ONO-6126

ONO-6126 is a PDE4 inhibitor that can be used in research for asthma and chronic obstructive pulmonary disease.

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CAS No.: 401519-28-6
Formule: C₂₀H₂₇N₃O₄
Masse moléculaire:373.45

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ONO-6126 Chemical Structure

CAS No.: 401519-28-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

ONO-6126 is a PDE4 inhibitor that can be used in research for asthma and chronic obstructive pulmonary disease^[1].

IC₅₀ & Target

PDE4

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE) :

Cellular Effect

Cell Line	Type	Value	Description	References
U-937	IC₅₀	0.08 nM Compound: 2b	Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cells Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cells	[PMID: 14684329]

Chemical Information

CAS No. 401519-28-6
Masse moléculaire 373.45
Formule C₂₀H₂₇N₃O₄
SMILES

N#CC1(CCN(CC1)CC(NO)=O)C2=CC=C(C(OC3CCCC3)=C2)OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Giembycz MA. Phosphodiesterase-4: selective and dual-specificity inhibitors for the therapy of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2005;2(4):326-33; discussion 340-1. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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ONO-6126

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

ONO-6126 Related Classifications

HY-121491 Related Classifications