Ormetoprim
Based on 1 Customer Validation
Ormetoprim is a veterinary antimicrobial which commonly used in aquaculture and poultry industries. Ormetoprim can be used to prevent the spread of disease in freshwater aquaculture and promote growth in farm animals.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.69%
- CAS No.: 6981-18-6
- Formule: C14H18N4O2
- Masse moléculaire:274.32
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Stockage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Ormetoprim (8.3 mg/kg; p.o.) exhibits absorption half-life (3.9 h), elimination half-life (3.9 h), Cmax (1.6±0.4 μg/mL) and oral availability (78.5%) relative to intraperitoneal administration[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Hybrid striped bass (565-805 g)[3]
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Dosage:50 mg/kg Sulfadimethoxine and Ormetoprim in a 5:1 ratio (Pharmacokinetic Analysis)
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Administration:I.p. and p.o. administration
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Result:I.p.: t1/2(elim)=7.5 h; t1/2(abs)=5.4 h; Cmax=1.2 μg/mL.
P.o.: t1/2(elim)=3.9 h; t1/2(abs)=3.9 h; Cmax=1.6 μg/mL; F=78.5%.
Chemical Information
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CAS No. 6981-18-6
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Appearance Solid
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Masse moléculaire 274.32
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Formule C14H18N4O2
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Color Off-white to light yellow
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SMILES
NC1=NC=C(CC2=CC(OC)=C(OC)C=C2C)C(N)=N1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
DMSO : 25 mg/mL (91.13 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Sanders SM, et, al. Sorption of the veterinary antimicrobials sulfadimethoxine and ormetoprim in soil. J Environ Qual. 2008 Jun 23; 37(4): 1510-8. [Content Brief]
[2]. Guerard JJ, et, al. Photodegradation of ormetoprim in aquaculture and stream-derived dissolved organic matter. J Agric Food Chem. 2012 Oct 3; 60(39): 9801-6. [Content Brief]
[3]. Bakal RS, et, al. Pharmacokinetics of sulfadimethoxine and ormetoprim in a 5:1 ratio following intraperitoneal and oral administration, in the hybrid striped bass (Morone chrysops x Morone saxitalis). J Vet Pharmacol Ther. 2004 Feb; 27(1): 1-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6454 mL | 18.2269 mL | 36.4538 mL | 91.1344 mL |
| 5 mM | 0.7291 mL | 3.6454 mL | 7.2908 mL | 18.2269 mL | |
| 10 mM | 0.3645 mL | 1.8227 mL | 3.6454 mL | 9.1134 mL | |
| 15 mM | 0.2430 mL | 1.2151 mL | 2.4303 mL | 6.0756 mL | |
| 20 mM | 0.1823 mL | 0.9113 mL | 1.8227 mL | 4.5567 mL | |
| 25 mM | 0.1458 mL | 0.7291 mL | 1.4582 mL | 3.6454 mL | |
| 30 mM | 0.1215 mL | 0.6076 mL | 1.2151 mL | 3.0378 mL | |
| 40 mM | 0.0911 mL | 0.4557 mL | 0.9113 mL | 2.2784 mL | |
| 50 mM | 0.0729 mL | 0.3645 mL | 0.7291 mL | 1.8227 mL | |
| 60 mM | 0.0608 mL | 0.3038 mL | 0.6076 mL | 1.5189 mL | |
| 80 mM | 0.0456 mL | 0.2278 mL | 0.4557 mL | 1.1392 mL |
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