PD-334581
Based on 1 Customer Validation
PD-334581 is a MEK1 inhibitor.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.72%
- CAS No.: 548756-68-9
- Formule: C20H19F3IN5O2
- Masse moléculaire:545.30
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Serine/Threonine Kinase Inhibitor Library
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Bioactive Compound Library
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Cell Proliferation Compound Library
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Posttranslational Modification Library
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Voir tous les produits spécifiques à Isoform MEK
More
Activité biologique
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MEK1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Colon 26 | IC50 |
0.032 M
Compound: 12J
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Inhibition of MEK in mouse Colon 26 cells by Western blot
Inhibition of MEK in mouse Colon 26 cells by Western blot
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[PMID: 18951019] |
Chemical Information
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CAS No. 548756-68-9
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Appearance Solid
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Masse moléculaire 545.30
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Formule C20H19F3IN5O2
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Color White to yellow
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SMILES
FC1=C(F)C(NC2=CC=C(C=C2F)I)=C(C3=NN=C(NCCN4CCOCC4)O3)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 12.5 mg/mL (22.92 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8339 mL | 9.1693 mL | 18.3385 mL | 45.8463 mL |
| 5 mM | 0.3668 mL | 1.8339 mL | 3.6677 mL | 9.1693 mL | |
| 10 mM | 0.1834 mL | 0.9169 mL | 1.8339 mL | 4.5846 mL | |
| 15 mM | 0.1223 mL | 0.6113 mL | 1.2226 mL | 3.0564 mL | |
| 20 mM | 0.0917 mL | 0.4585 mL | 0.9169 mL | 2.2923 mL |
PD-334581 Related Classifications
HY-107619 Related Classifications
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