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Cat. No.: HY-106430

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Piclozotan

(Synonyms: SUN N4057)

Piclozotan (SUN N4057) is a 5HT1A receptor agonist. Piclozotan improves motor complications in Parkinson's disease model.

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CAS No.: 182415-09-4
Formule: C₂₃H₂₄ClN₃O₂
Masse moléculaire:409.91

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Piclozotan Chemical Structure

CAS No.: 182415-09-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Description
- IC₅₀ & Target
- Essai clinique
Chemical Information
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Références
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Activité biologique

Description

Piclozotan (SUN N4057) is a 5HT1A receptor agonist. Piclozotan improves motor complications in Parkinson's disease model^[1].

IC₅₀ & Target^[1]

5-HT_1A Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 182415-09-4
Masse moléculaire 409.91
Formule C₂₃H₂₄ClN₃O₂
SMILES

O=C1C2=C(OC=C(N1CCCCN3CC=C(CC3)C4=CC=CC=N4)Cl)C=CC=C2
Synonyms

SUN N4057
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Tani Y, et al. Effects of piclozotan (SUN N4057), a partial serotonin 1A receptor agonist, on motor complications induced by repeated administration of levodopa in parkinsonian rats. Eur J Pharmacol. 2010 Dec 15;649(1-3):218-23. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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- IC₅₀ & Target
- Essai clinique
Chemical Information
Pureté et documentation
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Piclozotan

Voir tous les produits spécifiques à Isoform 5-HT Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Piclozotan Related Classifications

HY-106430 Related Classifications