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Cat. No.: HY-W1113770

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STAT6-IN-8

STAT6-IN-8 is a STAT6 inhibitor with an IC₅₀ of 0.45 μmol/L. STAT6-IN-8 exhibits potential anti-inflammatory and anti-allergic effects. STAT6-IN-8 can be used for the research of atopic dermatitis.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 3033741-50-0
Formule: C₂₉H₂₄F₄N₆O₃
Masse moléculaire:580.53

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

STAT6-IN-8 Chemical Structure

CAS No.: 3033741-50-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target^[1]

STAT6

0.45 μM (IC₅₀)

Voir tous les produits spécifiques à Isoform STAT :

In Vitro

STAT6-IN-8 (example 9) (0.1-1 μmol/L) inhibits STAT6 in HEK293 cells with inhibition rates of 10% and 76%, at 0.1 and 1 μmol/L, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3033741-50-0
Masse moléculaire 580.53
Formule C₂₉H₂₄F₄N₆O₃
SMILES

O=C(C1=C(F)C(NC(C2=CC(C(F)(F)F)=CC3=C2N(CC)C(C4=CC=C(N5C(N(C)N=C5C)=O)C=C4)=C3)=O)=CC=C1)N
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Fused ring compound and pharmaceutical containing same. WO2024071439A1.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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STAT6-IN-8

Voir tous les produits spécifiques à Isoform STAT

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

STAT6-IN-8 Related Classifications

HY-W1113770 Related Classifications