Thio-acridone
Thio-acridone (SACD) is a photosensitizer (HAF-PSs). Thio-acridone forms a long-lived triplet state upon excitation by 470 nm visible light,, ultimately generating singlet oxygen to damage the structures and functions of target cells such as cancer cells. Thio-acridone is promising for research of cancers. Thio-acridone is a CDK4/Cyclin D1 inhibitor (IC50 = 2 uM).
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- CAS No.: 6540-78-9
- Formule: C13H9NS
- Masse moléculaire:211.28
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
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Activité biologique
Description
IC50 & Target
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Cdk4/cyclin D1 2 μM (IC50) |
Chemical Information
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CAS No. 6540-78-9
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Masse moléculaire 211.28
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Formule C13H9NS
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SMILES
S=C1C2=C(NC3=C1C=CC=C3)C=CC=C2
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Synonyms
SACD
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thio-acridone Related Classifications
HY-171481 Related Classifications
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