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Vilobelimab

(Synonyms: CaCP-29, IFX-1)
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Based on 1 Customer Validation

Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc.

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  • Pureté: 99.27%
  • CAS No.: 2250440-41-4
  • Masse moléculaire:145.88 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vilobelimab
  • Experimental Validation Results for Vilobelimab
  • Experimental Validation Results for Vilobelimab
  • Vilobelimab Chemical Structure
    Vilobelimab Chemical Structure
CAS No.: 2250440-41-4
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Vilobelimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Complement C5/C5a Protein, Human, HY-P7864) can bind Vilobelimab. The EC50 for this effect is 14.20 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 HepG2 cells labeling Vilobelimab (HY-P99520, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/50 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Vilobelimab Chemical Structure
    1/16
  • Vilobelimab
  • Immobilized Complement C5/C5a Protein, Human, HY-P7864) can bind Vilobelimab. The EC50 for this effect is 14.20 ng/mL.
  • Flow cytometric analysis of 1X106 HepG2 cells labeling Vilobelimab (HY-P99520, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/50 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).