ZLY032
ZLY032 is a dual FFA1/PPARδ agonist with the activity of improving glucose and lipid metabolism, alleviating liver fibrosis, and potentially inhibiting metabolic disorders.
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- CAS No.: 2314465-67-1
- Formule: C22H18F3NO4S
- Masse moléculaire:449.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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HY-B0258
GemfibrozilCytochrome P450 Inhibitor -
HY-B0258R
Gemfibrozil (Standard) -
HY-101559
10-Nitrooleic acidNitro Fatty Acid -
HY-121457
9-NitrooleateNitrated Fatty Acid -
HY-119311
Ketopioglitazone -
HY-113473
10-Nitrolinoleic acidPPARγ Agonist -
HY-128171
DiflapolinFLAP/sEH Inhibitor -
HY-125143
ABC34Inactive Control of JJH260 -
HY-13956B
Pioglitazone potassiumPPARγ Agonist -
HY-113162A
Bovinic acid sodiumFatty Acid -
HY-131405
β-Eleostearic acidApoptosis Inducer
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
68 nM
Compound: 32
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Agonist activity at human FFA1 receptor expressed in CHO cells by Fluo 4-AM dye based FLIPR assay
Agonist activity at human FFA1 receptor expressed in CHO cells by Fluo 4-AM dye based FLIPR assay
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[PMID: 30605833] |
| HEK293 | EC50 |
>10 μM
Compound: 32
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Transactivation of GAL4-fused human PPARalpha LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
Transactivation of GAL4-fused human PPARalpha LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
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[PMID: 30605833] |
| HEK293 | EC50 |
>10 μM
Compound: 32
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Transactivation of GAL4-fused human PPARgamma LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
Transactivation of GAL4-fused human PPARgamma LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
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[PMID: 30605833] |
| HEK293 | EC50 |
102 nM
Compound: 32
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Transactivation of GAL4-fused human PPARdelta LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
Transactivation of GAL4-fused human PPARdelta LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
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[PMID: 30605833] |
Chemical Information
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CAS No. 2314465-67-1
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Masse moléculaire 449.44
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Formule C22H18F3NO4S
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SMILES
OC(C[C@H]1C2=CC=C(OCC3=C(C)N=C(C4=CC=C(C=C4)C(F)(F)F)S3)C=C2OC1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZLY032 Related Classifications
HY-139175 Related Classifications
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