CRBN ligand-11
Based on 1 Customer Validation
CRBN ligand-11 is the E3 ubiquitin ligase ligand for CFT8634 (HY-145925B). CRBN ligand-11 can be used for the synthesis of PROTACs.
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- Purity: 99.94%
- CAS No.: 2962967-27-5
- 화학식: C11H10BrFN2O2
- 분자량:301.11
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2962967-27-5
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Appearance Solid
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분자량 301.11
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화학식 C11H10BrFN2O2
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Color White to off-white
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SMILES
O=C(C(NC1=CC=C(Br)C(F)=C1)CC2)NC2=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
DMSO : 100 mg/mL (332.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3210 mL | 16.6052 mL | 33.2105 mL | 83.0261 mL |
| 5 mM | 0.6642 mL | 3.3210 mL | 6.6421 mL | 16.6052 mL | |
| 10 mM | 0.3321 mL | 1.6605 mL | 3.3210 mL | 8.3026 mL | |
| 15 mM | 0.2214 mL | 1.1070 mL | 2.2140 mL | 5.5351 mL | |
| 20 mM | 0.1661 mL | 0.8303 mL | 1.6605 mL | 4.1513 mL | |
| 25 mM | 0.1328 mL | 0.6642 mL | 1.3284 mL | 3.3210 mL | |
| 30 mM | 0.1107 mL | 0.5535 mL | 1.1070 mL | 2.7675 mL | |
| 40 mM | 0.0830 mL | 0.4151 mL | 0.8303 mL | 2.0757 mL | |
| 50 mM | 0.0664 mL | 0.3321 mL | 0.6642 mL | 1.6605 mL | |
| 60 mM | 0.0554 mL | 0.2768 mL | 0.5535 mL | 1.3838 mL | |
| 80 mM | 0.0415 mL | 0.2076 mL | 0.4151 mL | 1.0378 mL | |
| 100 mM | 0.0332 mL | 0.1661 mL | 0.3321 mL | 0.8303 mL |
CRBN ligand-11 Related Classifications
HY-169989 Related Classifications
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