Cucurbitacin Q1
Based on 1 Customer Validation
Cucurbitacin Q1 is a tetracyclic triterpene that can be found in Cucumis prophetarum.
For research use only. We do not sell to patients.
- Purity: 98.39%
- CAS No.: 99530-82-2
- Formula: C32H48O8
- Molecular Weight:560.72
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Natural Product Library
HY-L021
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Terpenoids Library
HY-L056
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Plant-Sourced Natural Product Library
HY-L115
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Natural Product Library Plus
HY-L021P
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Natural Product and Natural Product-Like Compound Library
HY-L021M
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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High-Throughput Natural Product Library
HY-L206
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Mass Spectrometry Natural Product Library
HY-L262
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | IC50 |
0.54 μM
Compound: 11
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Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay
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[PMID: 22239601] |
| MCF7 | GI50 |
0.11 μM
Compound: 3
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Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
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[PMID: 14640532] |
| NCI-H460 | GI50 |
0.065 μM
Compound: 3
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Cytotoxicity against human H460 cells
Cytotoxicity against human H460 cells
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[PMID: 14640532] |
| SF-268 | GI50 |
0.087 μM
Compound: 3
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Cytotoxicity against human SF268 cells
Cytotoxicity against human SF268 cells
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[PMID: 14640532] |
Chemical Information
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CAS No. 99530-82-2
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Appearance Solid
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Molecular Weight 560.72
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Formula C32H48O8
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Color White to off-white
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SMILES
C[C@@]([C@@](CC=C(C(C)([C@@H]1O)C)[C@@]2([H])C[C@@H]1O)([H])[C@@]32C)(C[C@H]4O)[C@@]([C@@]4([H])[C@@](C)(O)C(/C=C/C(C)(C)OC(C)=O)=O)(CC3=O)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 25 mg/mL (44.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1.25 mg/mL (2.23 mM); Clear solution
This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7834 mL | 8.9171 mL | 17.8342 mL | 44.5855 mL |
| 5 mM | 0.3567 mL | 1.7834 mL | 3.5668 mL | 8.9171 mL | |
| 10 mM | 0.1783 mL | 0.8917 mL | 1.7834 mL | 4.4586 mL | |
| 15 mM | 0.1189 mL | 0.5945 mL | 1.1889 mL | 2.9724 mL | |
| 20 mM | 0.0892 mL | 0.4459 mL | 0.8917 mL | 2.2293 mL | |
| 25 mM | 0.0713 mL | 0.3567 mL | 0.7134 mL | 1.7834 mL | |
| 30 mM | 0.0594 mL | 0.2972 mL | 0.5945 mL | 1.4862 mL | |
| 40 mM | 0.0446 mL | 0.2229 mL | 0.4459 mL | 1.1146 mL |
Cucurbitacin Q1 Related Classifications
HY-N8137 Related Classifications
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