country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-184407

Copy Link Print Information

D-AAP1

D-AAP1 is an RNA polymerase inhibitor. D-AAP1 exhibits anti-mycobacterial activity. D-AAP1 can be used for the research of mycobacterial infections.

For research use only. We do not sell to patients.

CAS No.: 1803030-41-2
Formula: C₂₃H₂₂N₂O₂
Molecular Weight:358.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

D-AAP1 Chemical Structure

CAS No.: 1803030-41-2

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

D-AAP1 is an RNA polymerase inhibitor. D-AAP1 exhibits anti-mycobacterial activity. D-AAP1 can be used for the research of mycobacterial infections^[1].

All DNA/RNA Synthesis Isoforms :

In Vitro

D-AAP1 inhibits Mycobacterium tuberculosis RNA polymerase by binding to the N-terminal bridge-helix and F-loop, with a mechanism distinct from rifamycins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1803030-41-2
Molecular Weight 358.43
Formula C₂₃H₂₂N₂O₂
SMILES

O=C([C@@H](CC1=CC=CC=C1)NC(C2=CC=CC=C2)=O)NC3=CC=CC=C3C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Doering J, et al. Cytochrome P450-Mediated Metabolism of Antimycobacterial Nα-Aroyl-N-aryl-phenylalanine Amides. ACS Infect Dis. 2026 Jun 12;12(6):1992-2003. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

D-AAP1

All DNA/RNA Synthesis Isoforms