1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Endogenous Metabolite
  3. D-Valine-d8

D-Valine-d8 is the deuterium labeled D-Valine. D-Valine is the enantiomer of L-Valine (HY-N0717). L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid.

For research use only. We do not sell to patients.

D-Valine-d<sub>8</sub> Chemical Structure

D-Valine-d8 Chemical Structure

CAS No. : 1116448-82-8

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5 mg USD 150 In-stock
10 mg USD 240 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

D-Valine-d8 is the deuterium labeled D-Valine. D-Valine is the enantiomer of L-Valine (HY-N0717). L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

125.20

Formula

C5H3D8NO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])[C@](N)([2H])C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 14.29 mg/mL (114.14 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.9872 mL 39.9361 mL 79.8722 mL
5 mM 1.5974 mL 7.9872 mL 15.9744 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.9872 mL 39.9361 mL 79.8722 mL 199.6805 mL
5 mM 1.5974 mL 7.9872 mL 15.9744 mL 39.9361 mL
10 mM 0.7987 mL 3.9936 mL 7.9872 mL 19.9681 mL
15 mM 0.5325 mL 2.6624 mL 5.3248 mL 13.3120 mL
20 mM 0.3994 mL 1.9968 mL 3.9936 mL 9.9840 mL
25 mM 0.3195 mL 1.5974 mL 3.1949 mL 7.9872 mL
30 mM 0.2662 mL 1.3312 mL 2.6624 mL 6.6560 mL
40 mM 0.1997 mL 0.9984 mL 1.9968 mL 4.9920 mL
50 mM 0.1597 mL 0.7987 mL 1.5974 mL 3.9936 mL
60 mM 0.1331 mL 0.6656 mL 1.3312 mL 3.3280 mL
80 mM 0.0998 mL 0.4992 mL 0.9984 mL 2.4960 mL
100 mM 0.0799 mL 0.3994 mL 0.7987 mL 1.9968 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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D-Valine-d8
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HY-N0717AS
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