1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Dabigatran ethyl ester

Dabigatran ethyl ester 

Cat. No.: HY-17378 Purity: 99.26%
Handling Instructions

Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity.

For research use only. We do not sell to patients.

Dabigatran ethyl ester Chemical Structure

Dabigatran ethyl ester Chemical Structure

CAS No. : 429658-95-7

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. IC50 value: Target: thrombin Dabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h; the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%.

Molecular Weight

499.56

Formula

C₂₇H₂₉N₇O₃

CAS No.

429658-95-7

SMILES

O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C(N)=N)C=C4)=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

References

Purity: 99.26%

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Product Name:
Dabigatran ethyl ester
Cat. No.:
HY-17378
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