1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Dabigatran (ethyl ester)

Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity.

For research use only. We do not sell to patients.

Dabigatran (ethyl ester) Chemical Structure

Dabigatran (ethyl ester) Chemical Structure

CAS No. : 429658-95-7

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Based on 1 publication(s) in Google Scholar

Other Forms of Dabigatran (ethyl ester):

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1 Publications Citing Use of MCE Dabigatran (ethyl ester)

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Description

Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. IC50 value: Target: thrombin Dabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h; the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%.

Molecular Weight

499.56

Formula

C27H29N7O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C(N)=N)C=C4)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : < 0.1 mg/mL (insoluble)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

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Purity & Documentation
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Dabigatran (ethyl ester) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Dabigatran (ethyl ester)
Cat. No.:
HY-17378
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