1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Dacisteine

Dacisteine (Synonyms: N,S-Diacetyl-L-cysteine)

Cat. No.: HY-121765
Handling Instructions

Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 μM. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation.

For research use only. We do not sell to patients.

Dacisteine Chemical Structure

Dacisteine Chemical Structure

CAS No. : 18725-37-6

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Description

Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 μM[1]. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation[2].

IC50 & Target

IC50: 1000 μM (NDM-1)[1]

In Vivo

Dacisteine is a preparing agent for treating or preventing cardiovascular and cerebrovascular diseases caused by platelet aggregation.

Molecular Weight

205.23

Formula

C₇H₁₁NO₄S

CAS No.

18725-37-6

SMILES

CC(SC[[email protected]@H](C(O)=O)NC(C)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (1218.15 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8726 mL 24.3629 mL 48.7258 mL
5 mM 0.9745 mL 4.8726 mL 9.7452 mL
10 mM 0.4873 mL 2.4363 mL 4.8726 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (10.13 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (10.13 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (10.13 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

DacisteineN,S-Diacetyl-L-cysteineEndogenous MetaboliteCysteinederivativeNDM-1cardiovascularcerebrovasculardiseaseplateletaggregationInhibitorinhibitorinhibit

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Dacisteine
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HY-121765
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