1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. ddGTP trisodium

ddGTP trisodium  (Synonyms: 2′,3′-Dideoxyguanosine 5′-triphosphate trisodium)

Cat. No.: HY-134103A Purity: ≥99.0%
COA Handling Instructions

ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) trisodium is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddGTP trisodium acts as an inhibitor or a substrate for DNA polymerase α.

For research use only. We do not sell to patients.

ddGTP trisodium Chemical Structure

ddGTP trisodium Chemical Structure

Size Price Stock Quantity
Solvent
2.79mg(100 mM * 50 μL in Water) USD 850 In-stock
Solvent
5.57mg(100 mM * 100 μL in Water) USD 1200 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) trisodium is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddGTP trisodium acts as an inhibitor or a substrate for DNA polymerase α[1][2][3].

In Vitro

ddGTP trisodium inhibits the formation of both negative and positive DNA strands[1]. ddGTP trisodium inhibits DNA polymerase α activity in the presence of Mn[2+] at low concentrations (<1 μM) [2]. ddGTP trisodium competitively inhibits the incorporation of [3H]dGTP into the DNA[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

557.13

Formula

C10H13N5Na3O12P3

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=[P](O[P](O[P](O)(O[Na])=O)(O[Na])=O)(O[Na])OC[C@@H]1CC[C@H](N2C(NC(N)=NC3=O)=C3N=C2)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation

Purity: ≥99.0%

References
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ddGTP trisodium Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ddGTP trisodium
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HY-134103A
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