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Cat. No.: HY-109053A

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Delgocitinib ethanolate

(Synonyms: JTE-052 ethanolate)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Delgocitinib ethanolate is a specific JAK inhibitor with IC₅₀s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively.

For research use only. We do not sell to patients.

CAS No.: 2064338-33-4
Formula: C₁₈H₂₄N₆O₂
Molecular Weight:356.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Delgocitinib ethanolate Chemical Structure

CAS No.: 2064338-33-4

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Fluorescent Dye

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Biological Activity

Description

Delgocitinib ethanolate is a specific JAK inhibitor with IC₅₀s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively^[1].

All JAK Isoforms :

Chemical Information

CAS No. 2064338-33-4
Molecular Weight 356.42
Formula C₁₈H₂₄N₆O₂
SMILES

CCO.N#CCC(N1[C@]2([C@H](C1)C)CN(C3=C4C(NC=C4)=NC=N3)CC2)=O
Synonyms

JTE-052 ethanolate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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J Clin Med

Aryl Hydrocarbon Receptor Activation Downregulates IL-33 Expression in Keratinocytes via Ovo-Like 1. [Abstract]

2020 Mar 24;9(3):891. PMID: 32214018
bioRxiv

2025 February 21.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tanimoto A, et al. Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo. Inflamm Res. 2015 Jan;64(1):41-51. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Delgocitinib ethanolate

2 Cited Publications

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Biological Activity
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Publications (2)
Purity & Documentation
References

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Delgocitinib ethanolate

Publications Citing Use of MedChemExpress (MCE) Delgocitinib ethanolate

All JAK Isoforms

Biological Activity

Chemical Information

Publications (2)

Purity & Documentation

References

Calculators

Help & FAQs

Delgocitinib ethanolate Related Classifications

HY-109053A Related Classifications