DHODH-IN-20
DHODH-IN-20 (Compound 133) is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-20 inhibits tumor growth. DHODH-IN-20 has the potential for the research of acute myelogenous leukemia.
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- CAS No.: 2639835-02-0
- 화학식: C24H25F4N3O3
- 분자량:479.47
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MOLM-13 | IC50 |
0.02 nM
Compound: 133
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Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell viability measured for 72 hrs by cell titer glo assay
Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell viability measured for 72 hrs by cell titer glo assay
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[PMID: 35178168] |
Chemical Information
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CAS No. 2639835-02-0
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분자량 479.47
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화학식 C24H25F4N3O3
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SMILES
O=C(NC1=CC=CC=C1C)C2=CC(F)=C(C3=CN(C)C(C(C)(O)C)=N3)C=C2O[C@@H](C)C(F)(F)F
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DHODH-IN-20 Related Classifications
HY-144371 Related Classifications
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