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Cat. No.: HY-121491

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ONO-6126

ONO-6126 is a PDE4 inhibitor that can be used in research for asthma and chronic obstructive pulmonary disease.

For research use only. We do not sell to patients.

CAS No.: 401519-28-6
Formula: C₂₀H₂₇N₃O₄
Molecular Weight:373.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ONO-6126 Chemical Structure

CAS No.: 401519-28-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ONO-6126 is a PDE4 inhibitor that can be used in research for asthma and chronic obstructive pulmonary disease^[1].

IC₅₀ & Target

PDE4

All Phosphodiesterase (PDE) Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
U-937	IC₅₀	0.08 nM Compound: 2b	Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cells Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cells	[PMID: 14684329]

Chemical Information

CAS No. 401519-28-6
Molecular Weight 373.45
Formula C₂₀H₂₇N₃O₄
SMILES

N#CC1(CCN(CC1)CC(NO)=O)C2=CC=C(C(OC3CCCC3)=C2)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Giembycz MA. Phosphodiesterase-4: selective and dual-specificity inhibitors for the therapy of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2005;2(4):326-33; discussion 340-1. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ONO-6126

All Phosphodiesterase (PDE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ONO-6126 Related Classifications

HY-121491 Related Classifications