Tibolone-d5
Tibolone-d5 is deuterium labeled Tibolone. Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research.
For research use only. We do not sell to patients.
- Formula: C21H23D5O2
- Molecular Weight:317.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled Cas 5630-53-5
-
Molecular Weight 317.48
-
Formula C21H23D5O2
-
SMILES
C[C@]([C@@](O)(C([2H])([2H])C1)C#C)(CC[C@]2([H])C3=C(CC(CC3)=O)C4)[C@]1([H])[C@]2([H])[C@@H]4C([2H])([2H])[2H]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Dragos Apostu, et al. Tibolone, alendronate, and simvastatin enhance implant osseointegration in a preclinical in vivo model. Clin Oral Implants Res. 2020 Jul;31(7):655-668. [Content Brief]
[3]. Marcos García-Juárez, et al. Tibolone induces lordosis behavior, but not concurrent or sequential inhibition, in Sprague Dawley rats. Neurosci Lett. 2021 Apr 24;755:135916. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)