1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. iGluR
  3. DQP-1105

DQP-1105 

Cat. No.: HY-107711 Purity: 98.10%
COA Handling Instructions

DQP-1105 is a potent noncompetitive NMDA receptor antagonist. DQP-1105 inhibits GluN2C- and GluN2D-containing receptors (IC50=7.0 and 2.7 μM, respectively). The IC50 values are at least 50-fold lower than those for recombinant GluN2A-, GluN2B-, GluA1-, or GluK2-containing receptors.

For research use only. We do not sell to patients.

DQP-1105 Chemical Structure

DQP-1105 Chemical Structure

CAS No. : 380560-89-4

Size Price Stock Quantity
5 mg USD 105 In-stock
10 mg USD 180 In-stock
25 mg USD 380 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

DQP-1105 is a potent noncompetitive NMDA receptor antagonist. DQP-1105 inhibits GluN2C- and GluN2D-containing receptors (IC50=7.0 and 2.7 μM, respectively). The IC50 values are at least 50-fold lower than those for recombinant GluN2A-, GluN2B-, GluA1-, or GluK2-containing receptors[1].

Molecular Weight

558.42

Formula

C29H24BrN3O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CCC(N1N=C(CC1C2=CC=C(C=C2)Br)C3=C(C4=CC=CC=C4)C5=C(C=CC(C)=C5)NC3=O)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (17.91 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7908 mL 8.9538 mL 17.9077 mL
5 mM 0.3582 mL 1.7908 mL 3.5815 mL
10 mM 0.1791 mL 0.8954 mL 1.7908 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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DQP-1105 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
DQP-1105
Cat. No.:
HY-107711
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