1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. (E)-10-Hydroxynortriptyline

(E)-10-Hydroxynortriptyline  (Synonyms: E-10-OH-NT)

Cat. No.: HY-U00050 Purity: 99.66%
COA Handling Instructions

(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline (HY-B0527A). E-10-OH-NT is about 50% as potent as nortriptyline as an inhibitor of the neuronal uptake of norepinephrine in vitro and exhibits less anticholinergic effects in man.

For research use only. We do not sell to patients.

(E)-10-Hydroxynortriptyline Chemical Structure

(E)-10-Hydroxynortriptyline Chemical Structure

CAS No. : 47132-16-1

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5 mg USD 630 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

Other Forms of (E)-10-Hydroxynortriptyline:

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Description

(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline (HY-B0527A)[1]. E-10-OH-NT is about 50% as potent as nortriptyline as an inhibitor of the neuronal uptake of norepinephrine in vitro and exhibits less anticholinergic effects in man.

Molecular Weight

279.38

Formula

C19H21NO

CAS No.
SMILES

OC1C2=CC=CC=C2/C(C3=CC=CC=C3C1)=C/CCNC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 3.57 mg/mL (12.78 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5794 mL 17.8968 mL 35.7935 mL
5 mM 0.7159 mL 3.5794 mL 7.1587 mL
10 mM 0.3579 mL 1.7897 mL 3.5794 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(E)-10-Hydroxynortriptyline
Cat. No.:
HY-U00050
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