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Cat. No.: HY-N19772

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Echiguanine B

Echiguanine B is a phosphatidylinositol-4-kinase (PI4K) inhibitor with an IC₅₀ of 0.11 μg/mL against human targets. Echiguanine B inhibits phosphatidylinositol-4-kinase activity in the cell membranes of epithelial cancer cells. Echiguanine B can be used in cancer-related research.

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CAS No.: 137319-26-7
Formule: C₁₀H₁₄N₆O₂
Masse moléculaire:250.26

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Please store the product under the recommended conditions in the Certificate of Analysis.

Echiguanine B Chemical Structure

CAS No.: 137319-26-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

IC₅₀ & Target^[1]

PI4K

0.11 μg/mL (IC₅₀)

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In Vitro

Echiguanine B (20 min at 20°C) inhibits phosphatidylinositol-4-kinase from A431 cell membranes with an IC₅₀ of 0.11 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 137319-26-7
Masse moléculaire 250.26
Formule C₁₀H₁₄N₆O₂
SMILES

O=C1N=C(NC2=C1C(C(NCCCN)=O)=CN2)N
Structure Classification
- Others
Initial Source
- Microorganisms
STREPTOMYCES SP.
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Nishioka H, et al. Isolation and structure determination of novel phosphatidylinositol kinase inhibitors, echiguanines A and B, from Streptomyces sp. Journal of natural products. 1991;54(5):1321-5. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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Echiguanine B

Voir tous les produits spécifiques à Isoform PI4K

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Echiguanine B Related Classifications

HY-N19772 Related Classifications