2. PI3K/Akt/mTOR
  3. PI4K
  4. Echiguanine B

Echiguanine B is a phosphatidylinositol-4-kinase (PI4K) inhibitor with an IC50 of 0.11 μg/mL against human targets. Echiguanine B inhibits phosphatidylinositol-4-kinase activity in the cell membranes of epithelial cancer cells. Echiguanine B can be used in cancer-related research.

For research use only. We do not sell to patients.

Echiguanine B

Echiguanine B Chemical Structure

CAS No. : 137319-26-7

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Echiguanine B Related Antibodies

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Description

Echiguanine B is a phosphatidylinositol-4-kinase (PI4K) inhibitor with an IC50 of 0.11 μg/mL against human targets. Echiguanine B inhibits phosphatidylinositol-4-kinase activity in the cell membranes of epithelial cancer cells. Echiguanine B can be used in cancer-related research[1].

IC50 & Target[1]

PI4K

0.11 μg/mL (IC50)

In Vitro

Echiguanine B (20 min at 20°C) inhibits phosphatidylinositol-4-kinase from A431 cell membranes with an IC50 of 0.11 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Echiguanine B Related Antibodies
Molecular Weight

250.26

Formula

C10H14N6O2
CAS No.
SMILES

O=C1N=C(NC2=C1C(C(NCCCN)=O)=CN2)N
Structure Classification
Initial Source

STREPTOMYCES SP.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Echiguanine B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Echiguanine B137319-26-7PI4KPhosphatidylinositol 4 kinasesPI4 kinasesepithelial cancer cell membranesmicephosphatidylinositol-4-kinaseA431 cell membranesInhibitorinhibitorinhibit

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