Eleven-Nineteen-Leukemia Protein IN-2
Eleven-Nineteen-Leukemia Protein IN-2 (compound 23) is an Eleven-Nineteen-Leukemia Protein (ENL) inhibitor with an IC50 value of 10.7 nM. Eleven-Nineteen-Leukemia Protein IN-2 can be used for the research of leukemia.
For research use only. We do not sell to patients.
- CAS No.: 2894121-78-7
- Formula: C22H23N5O2
- Molecular Weight:389.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MOLM-13 | IC50 |
37.9 μM
Compound: 23
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Antiproliferative activity against human MOLM-13 cells assessed as inhibition of cell growth measured after 72 hrs by Cell Titer-Glo luminescent assay
Antiproliferative activity against human MOLM-13 cells assessed as inhibition of cell growth measured after 72 hrs by Cell Titer-Glo luminescent assay
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[PMID: 36645983] |
| MV4-11 | IC50 |
51.4 μM
Compound: 23
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Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth measured after 72 hrs by Cell Titer-Glo luminescent assay
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth measured after 72 hrs by Cell Titer-Glo luminescent assay
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[PMID: 36645983] |
Eleven-Nineteen-Leukemia Protein IN-2 (0-1000 nM) shows ENL inhibitory activity with an IC50 value of 10.7 nM[1]. Eleven-Nineteen-Leukemia Protein IN-2 (0-1000 μM; 72 hours) inhibits activity of MOLM-13 cells with an IC50 value of 37.9 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2894121-78-7
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Molecular Weight 389.45
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Formula C22H23N5O2
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SMILES
CC1=NOC2=CC(C(NC3=CC=C4NC(CN5CCC[C@@H]5C)=NC4=C3)=O)=CC=C21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Eleven-Nineteen-Leukemia Protein IN-2 Related Classifications
HY-152470 Related Classifications
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