ERα ligand 6
ERα ligand 6 is an amino intermediate derived from OBHSA, and also serves as a precursor for the synthesis of ERα-targeted hydrophobic tag degraders, such as the ERα ligand moiety of ERα/RAD51 degrader 1 (HY-187096).
For research use only. We do not sell to patients.
- Formula: C29H26F3NO8S
- Molecular Weight:605.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
ERα |
In Vitro
ERα ligand 6 is an amino intermediate derived from OBHSA, which serves as the ERα ligand moiety of ERα/RAD51 degrader 1 (HY-187096). ERα/RAD51 degrader 1 is a HyT degrader targeting ERα and RAD51, which drives the degradation of ERα and RAD51 via the ubiquitin-proteasome pathway. ERα/RAD51 degrader 1 acts on both Tamoxifen (HY-13757A)-sensitive and Tamoxifen-resistant breast cancer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 605.58
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Formula C29H26F3NO8S
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SMILES
O=S(N(C1=CC=C(C=C1)OCCC(O)=O)CC(F)(F)F)(C2C[C@@H]3C(C4=CC=C(O)C=C4)=C(C5=CC=C(O)C=C5)[C@H]2O3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ERα ligand 6 Related Classifications
HY-187621 Related Classifications
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