Fenethazine
Fenethazine (Phenethazine) is a compound with antihistamine activity. It is an effective antihistamine. Its congeners also have anticholinergic effects and can be used to inhibit Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 522-24-7
- Formula: C16H18N2S
- Molecular Weight:270.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histamine Receptor Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 522-24-7
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Molecular Weight 270.39
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Formula C16H18N2S
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SMILES
CN(C)CCN1C2=C(SC3=CC=CC=C13)C=CC=C2
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Synonyms
Phenethazine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Human pluripotent stem cell midbrain dopaminergic neuron differentiation
Human pluripotent stem cells are directed toward midbrain dopaminergic neurons by first inducing a neural floor-plate-like progenitor state, then patterning cells with ventralizing SHH signaling and midbrain/WNT-FGF cues, and finally maturing progenitors into neurons expressing dopaminergic markers such as TH, NURR1/NR4A2, PITX3, DAT/SLC6A3, VMAT2/SLC18A2, GIRK2/KCNJ6, FOXA2, LMX1A, and EN1. The main readouts are loss of pluripotency, acquisition of FOXA2+/LMX1A+ midbrain floor-plate progenitors, emergence of βIII-tubulin+/MAP2+ neurons, and production of TH+ dopaminergic neurons with molecular, dopamine-release, and electrophysiological features of midbrain dopaminergic identity.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)