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Cat. No.: HY-117218

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KY-04045

KY-04045 is a PAK4 specific inhibitor (IC₅₀=8.7 μM) that can be used for the development of anticancer drugs targeting PAK4.

For research use only. We do not sell to patients.

CAS No.: 1223284-75-0
Formula: C₁₃H₁₄BrN₅
Molecular Weight:320.19

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

KY-04045 Chemical Structure

CAS No.: 1223284-75-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

KY-04045 is a PAK4 specific inhibitor (IC₅₀=8.7 μM) that can be used for the development of anticancer drugs targeting PAK4^[1].

IC₅₀ & Target^[1]

PAK4

8.7 μM (IC₅₀)

All PAK Isoforms :

Chemical Information

CAS No. 1223284-75-0
Molecular Weight 320.19
Formula C₁₃H₁₄BrN₅
SMILES

CC(C1=NN(C)C=C1C2=NC3=CC(Br)=CN=C3N2)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Park, et al. "The discovery and the structural basis of an imidazo [4, 5-b] pyridine-based p21-activated kinase 4 inhibitor." Bioorganic & medicinal chemistry letters 26.11 (2016): 2580-2583. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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KY-04045

All PAK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KY-04045 Related Classifications

HY-117218 Related Classifications