SP4f
Based on 1 Customer Validation
SP4f is an activator ofPPAR-γ, with the EC50 of 826 nM in HK-2 cells. SP4f reduces the blood glucose levels and lipid peroxidation, and increases glutathione levels and catalase activityin the Swiss albino mice.
For research use only. We do not sell to patients.
- Purity: 99.77%
- CAS No.: 3086376-13-5
- Formula: C22H17ClN2O2S2
- Molecular Weight:440.97
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
826 nM (PPAR-γ in the HK-2 cells)[1]
Chemical Information
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CAS No. 3086376-13-5
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Appearance Solid
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Molecular Weight 440.97
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Formula C22H17ClN2O2S2
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Color Yellow to orange
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SMILES
O=C(N(CC1=CC=C(C)C=C1)C/2=O)SC2=C/C3=CC=C(NC4=CC=CC(Cl)=C4)S3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20 mg/mL (45.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2677 mL | 11.3386 mL | 22.6773 mL | 56.6932 mL |
| 5 mM | 0.4535 mL | 2.2677 mL | 4.5355 mL | 11.3386 mL | |
| 10 mM | 0.2268 mL | 1.1339 mL | 2.2677 mL | 5.6693 mL | |
| 15 mM | 0.1512 mL | 0.7559 mL | 1.5118 mL | 3.7795 mL | |
| 20 mM | 0.1134 mL | 0.5669 mL | 1.1339 mL | 2.8347 mL | |
| 25 mM | 0.0907 mL | 0.4535 mL | 0.9071 mL | 2.2677 mL | |
| 30 mM | 0.0756 mL | 0.3780 mL | 0.7559 mL | 1.8898 mL | |
| 40 mM | 0.0567 mL | 0.2835 mL | 0.5669 mL | 1.4173 mL |