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Referencia número: HY-148172

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L-Fd4A

L-Fd4A is an adenine derivative. L-Fd4A has anti-human immunodeficiency virus (HIV) (EC₅₀=1.5 μM) and anti-hepatitis B virus (HBV) (EC₅₀=1.7 μM) activity. L-Fd4A has low cytotoxicity.

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No. CAS: 210474-65-0
Fòrmula: C₁₀H₁₀FN₅O₂
Peso molecular:251.22

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

L-Fd4A Chemical Structure

No. CAS: 210474-65-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Descripciòn
- Cellular Effect
- In Vitro
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Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas HIV :

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	>100 μM Compound: 36	Inhibitory activity was evaluated on mitochondrial DNA content of CEM cells Inhibitory activity was evaluated on mitochondrial DNA content of CEM cells	[PMID: 10197975]
PBMC	IC₅₀	>100 μM Compound: 36	Inhibitory activity was evaluated in human peripheral blood mononuclear (PBM) cells infected with Human immunodeficiency virus-1 Inhibitory activity was evaluated in human peripheral blood mononuclear (PBM) cells infected with Human immunodeficiency virus-1	[PMID: 10197975]
Vero	IC₅₀	>100 μM Compound: 36	Inhibitory activity was evaluated in Vero cells. Inhibitory activity was evaluated in Vero cells.	[PMID: 10197975]

In Vitro

L-Fd4A (compound 36) has no toxicity in PBM, Vero and CEM cells. L-Fd4A shows any effect on mitochondrial DNA of CEM cells upon long-term exposure^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 210474-65-0
Peso molecular 251.22
Fòrmula C₁₀H₁₀FN₅O₂
SMILES

OC[C@@H]1O[C@H](N2C3=NC=NC(N)=C3N=C2)C(F)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Lee K, et, al. Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides. J Med Chem. 1999 Apr 8;42(7):1320-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Actividad biológica
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Chemical Information
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L-Fd4A

Ver todos los productos específicos de isoformas HIV

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

L-Fd4A Related Classifications

HY-148172 Related Classifications