Facinicline
Facinicline (RG3487) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM.
For research use only. We do not sell to patients.
- CAS No.: 677306-35-3
- Formula: C15H18N4O
- Molecular Weight:270.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 677306-35-3
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Molecular Weight 270.33
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Formula C15H18N4O
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SMILES
O=C(C1=NNC2=C1C=CC=C2)N[C@@H]3CN4CCC3CC4
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Synonyms
RG3487 free base
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)