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Facinicline

(Synonyms: RG3487 free base)

Facinicline (RG3487) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM.

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  • CAS No.: 677306-35-3
  • 화학식: C15H18N4O
  • 분자량:270.33
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Facinicline Chemical Structure
    Facinicline Chemical Structure
CAS No.: 677306-35-3
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All 5-HT Receptor Isoforms

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  • Facinicline Chemical Structure
    Facinicline Chemical Structure
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  • Facinicline