Facinicline
Facinicline (RG3487) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM.
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- CAS No.: 677306-35-3
- Formule: C15H18N4O
- Masse moléculaire:270.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 677306-35-3
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Masse moléculaire 270.33
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Formule C15H18N4O
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SMILES
O=C(C1=NNC2=C1C=CC=C2)N[C@@H]3CN4CCC3CC4
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Synonyms
RG3487 free base
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)