Facinicline

(Synonyms: RG3487 free base)

Facinicline (RG3487) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM.

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  • CAS No.: 677306-35-3
  • Formule: C15H18N4O
  • Masse moléculaire:270.33
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    Please store the product under the recommended conditions in the Certificate of Analysis.

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