FGFR-IN-17
FGFR-IN-17 (Compound 12l) is an orally active irreversible inhibitor of FGFR, which has a strong inhibitory effect on FGFR and its mutants. FGFR-IN-17 can inhibit the proliferation and migration, and induce apoptosis of non-small cell lung cancer cells. FGFR-IN-17 has anti-tumor activity.
For research use only. We do not sell to patients.
- Formula: C26H29Cl2N7O2
- Molecular Weight:542.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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FGFR1 7.24 nM (IC50) |
FGFR2 15.6 nM (IC50) |
FGFR3 19.4 nM (IC50) |
FGFR4 486 nM (IC50) |
Chemical Information
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Molecular Weight 542.46
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Formula C26H29Cl2N7O2
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SMILES
C=CC(NC1=CC=C(NC2=NC(NC3=CC=C(N4C[C@@H](C)N[C@@H](C)C4)C(OC)=C3)=NC=C2Cl)C=C1Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FGFR-IN-17 Related Classifications
HY-172251 Related Classifications
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