KAT6A/KAT7-IN-3
KAT6A/KAT7-IN-3 is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-3 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-3 also inhibits tumor cell proliferation and can be used in the study of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3092066-83-3
- Formula: C24H24N4O6S
- Molecular Weight:496.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
KAT6A/KAT7-IN-3 (Compound Example 191) inhibits KAT6A, KAT7, K14 and K23 with IC50 values of 10-50 nM, ≤1 nM, 1-10 nM and 0.5-1 μM[1].
KAT6A/KAT7-IN-3 inhibits tumor cell proliferation, with an IC50 of > 2 μM and ≤ 5 μM for CAMA-1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3092066-83-3
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Molecular Weight 496.54
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Formula C24H24N4O6S
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SMILES
O=S(C1=C(OC)C=CN=C1OC)(NC2=NOC3=C2CC4(C5=C3C=C(N6C(CCC6)=O)C=C5)CC4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)